United States · Editorial service summary
Sesame weight loss review: Success by Sesame cost, medicines and Costco pricing
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Sesame: From $59/mo on an annual plan (10% off for Costco members). GLP-1 prescriptions incl. the Wegovy pill.
Low-cost self-pay program with Costco pharmacy pricing. A factual look at the service's published brand-name medicine path, fees and insurance help, not a patient rating.
Best for: Self-pay patients, including Costco members, who want a low advertised program fee and cash prices at Costco Pharmacy for brand-name medicines.
Key facts
| Who it may serve | Self-pay patients, including Costco members, who want a low monthly program fee. |
|---|---|
| States | The reviewed Sesame pages do not give a state list. Check availability on its site. |
| How the visit works | Sesame says the program includes video visits with a licensed clinician, a dedicated provider, lab work and messaging. |
| Medicines listed | Sesame says members can get prescriptions for weight-loss medicines such as GLP-1s. Its program announcement describes pricing for Wegovy injections, Ozempic injections and the Wegovy pill, and its semaglutide page also names Zepbound, Foundayo, Saxenda and Contrave as options a clinician may discuss. Ozempic is FDA-approved for type 2 diabetes; prescribing it for weight loss is off-label. Its semaglutide page also says compounded semaglutide is not currently available through Sesame. This review covers only branded, FDA-approved options. |
| After a prescription | Sesame says members with a prescription can self-pay $349/month for Wegovy or Ozempic injections at Costco Pharmacy, and that the Wegovy pill is available from $149/month. |
| Insurance | The reviewed pages describe self-pay pricing and do not describe insurance billing for the program. Ask before you join. |
| Care fees (USD) | Program priced from $59/month with an annual subscription; Sesame says Costco members get 10% off the program. Medication is extra. The $59 figure is the official annual-subscription price we could reconfirm today; other billing intervals should be confirmed on Sesame’s checkout. |
Read on official public pages 10 November 2026. Prices and availability can change.
Medicine prices on top of the fee
Care fees above do not include the medicine. For reference, these are the manufacturers' own self-pay prices; the price you pay through any program or pharmacy may differ.
Verified 10 November 2026.
| Medicine | Self-pay price per month | What one month means | Source |
|---|---|---|---|
| Wegovy pillsemaglutide tablets | 1.5 mg $149 · 4 mg $199 · 9 mg $299 · 25 mg $299 | 1 bottle of 30 tablets | Wegovy cost & coverage (Novo Nordisk) ↗ |
| Wegovy pensemaglutide injection | $199 for each of the first 2 months at 0.25 mg or 0.5 mg (intro offer for new patients, through 31 Dec 2026), then $349 · Wegovy HD 7.2 mg pen $399 · needles included | 1 box of 4 pens | Wegovy cost & coverage (Novo Nordisk) ↗ |
| Zepbound KwikPen or single-dose vialtirzepatide injection | 2.5 mg $299 · 5 mg $399 · 7.5–15 mg $449 if refilled within 45 days (otherwise $499 for 7.5 mg, $699 for 10–15 mg) | 28 days | LillyDirect: Zepbound self-pay ↗ |
| Foundayoorforglipron tablets | From $149 (0.8 mg). Lilly's regular prices: 0.8 mg $149 · 2.5 mg $199 · 5.5 mg and 9 mg $299 · 14.5 mg and 17.2 mg $349, or $299 if refilled within 45 days. Check Lilly's page for any limited-time changes | 30 days | Foundayo coverage & savings (Lilly) ↗ |
What to clarify first
The lowest program price requires an annual subscription. Confirm renewal and cancellation terms, and which medicines the clinician can prescribe in your state. Compounded semaglutide is not currently available through Sesame; we do not promote compounded GLP-1s.
- Can a clinician licensed in your state assess you, and do you meet the program's eligibility rules?
- What is the full ongoing cost, including medication, labs and any prepaid commitment?
- How do you contact the clinical team, and what happens if treatment is not suitable?
Pros
- The program is advertised from $59/month with an annual subscription and includes video visits, labs and messaging.
- Costco members get 10% off the program. Members with a prescription can self-pay $349/month for Wegovy or Ozempic injections at Costco Pharmacy, and the Wegovy pill is listed from $149/month.
- Sesame’s semaglutide page says compounded semaglutide is not currently available through Sesame.
Cons
- The $59 price is tied to an annual subscription; confirm cancellation and renewal terms before you pay.
- The reviewed pages describe self-pay pricing and do not describe insurance billing for the program.
- Ozempic is a type 2 diabetes medicine; prescribing it for weight loss is off-label. A state list is not published on the pages we reviewed.
Our take
Use the published facts to compare the care model with your needs, then confirm the details directly. We have not used this service as patients and publish no scores. A US-licensed clinician, not this site, decides whether a medicine is appropriate. Prescription approval is not guaranteed.
Compare all 8 US services · GLP-1 cost with or without insurance · Wegovy pill vs Foundayo · LillyDirect
What experts have said publicly
These are cited public statements, quoted as they appeared in the linked source. The experts have not reviewed or endorsed this site or any provider listed here.
“This is by far the most effective intervention we have seen for weight management when you compare it to many of the currently existing drugs.”
“Semaglutide sets the bar for a new generation of more effective weight-loss medications.”
“The oral option could improve long-term adherence by offering patients a non-injectable alternative with similar metabolic benefits.”
“We need ways to keep patients on these medicines long term, and an effective oral preparation could help us do that.”
Frequently asked questions
How much is Success by Sesame?
Sesame prices the program from $59/month with an annual subscription. Costco members get 10% off the program. Medication is extra.
Does Sesame offer compounded GLP-1s?
Sesame’s semaglutide page says compounded semaglutide is not currently available through Sesame. This review covers only branded, FDA-approved options.
What do Wegovy or Ozempic injections cost at Costco Pharmacy?
Sesame says members with a prescription can self-pay $349/month for Wegovy or Ozempic injections at Costco Pharmacy. A Costco membership and an active prescription apply; confirm current pharmacy terms.
Official sources
- Sesame: Costco weight-loss program update (page dated 6 Jan 2026) ↗ — checked 10 November 2026.
- Costco members: Ozempic and Wegovy pricing through Sesame ↗ — checked 10 November 2026.
- Sesame semaglutide page (compounded-semaglutide status and branded options) ↗ — checked 10 November 2026.
- Wegovy cost & coverage (Novo Nordisk) ↗ — checked 10 November 2026.
- LillyDirect: Zepbound self-pay ↗ — checked 10 November 2026.
- Foundayo coverage & savings (Lilly) ↗ — checked 10 November 2026.